Zoom satellite symposium in the frame of TECHVAC2020, July 22, 2020

VIRAL INFECTIONS AND CANCER, OPENINGS FOR VACCINES

15.00-16.40 Development of vaccines against viral infections and cancer

  1. Kostyshev Dmitry (National Medical Research Center of Tuberculosis and Infectious Diseases, Moscow, Russia) Stimulation of innate immunity by deep learning designed sgRNAs, implications for viral therapy and immunotherapy Contact mail: dkostushev@gmail.com
  1. Gordeychuk Ilya (Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia) Applicability of marmoset model for clinical trials of viral and cancer vaccines Contact mail: labgord@gmail.com
  1. Oleg Latyshev & Bayurova Ekaterina (Gamaleya National Research Center for Epidemiology and Microbiology, Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia) Immunogenicity of tumor associated antigen telomerase reverse transcriptase (TERT) in experimental animals. Contact mail: 79153645941@ya.ru
  1. Avdoshina Darya (Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia) Opposite effects of telomerase reverse transcriptase and HIV reverse transcriptase on the tumorigenic potential of expressing cells, possible underlying mechanisms Contact mail: darya_avdoshina@mail.ru
  1. Gromov Konstantin & Laga Vita (Gamaleya Research Center for Epidemiology and Microbiology, and MVA by K.I. Skryabin, Moscow, Russia) Polymorphisms of genes of HIV-1 clade A A6 sub-subtype widespread in Russia, current situation Contact mail: vita15laga@gmal.com; vita.laga@mail.ru

16.50-18.30 Papilloma Viruses, informing design of HPV vaccines

(6) Lebedeva Natalya (Moscow Regional Center for control and prevention of AIDS and communicable Diseases, and Gamaleya Research Center for Epidemology and Microbiology, Moscow, Russia) Dynamics of recurrence of human papilloma viruses of high carcinogenic risk in cervical smears of HIV infected women of the Moscow Region. Contact mail: lebedevanatalya@rocketmail.com <lebedevanatalya@rocketmail.com>

(7) Nosik Marina (Mechnikov Institute of Vaccine and Sera, Moscow, Russia) Detection rate of human papilloma viruses of high carcinogenic risk in women with HIV/TB co-infection. Contact mail: Nossik Marina <mnossik@yandex.ru>

(8) Petrakova Natalia & Nosik Marina (Gamaleya Research Center for Epidemiology and Microbiology, and Mechnikov Institute of Vaccine and Sera, Moscow, Russia) Socio-demographic characteristics of HIV/TB co-infected as correlates of infection with human papillomaviruses of high oncogenic risk. Contact mail: Nossik Marina <mnossik@yandex.ru>

(9) Karlsen Anastasya (Russian Medical Academy of Continuous Professional Education, and Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia) Features of protein sequences of E5, E6, E7 of HPV 16 detected in HIV-positive people in the Russian Federation. Contact mail: Анастасия Карлсен karlsen12@gmail.com, Maria Isaguliants maria.issagouliantis@ki.se

(10) Avdoshina Darya & Bayurova Ekaterina (Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, and Gamaleya Research Center of Epidemiology and Microbiology, Moscow, Russia) Generation and characteristics of 4T1 murine adenocarcinoma cell lines expressing E6 and E7 oncoproteins of HPV 16 as a model for testing HPV 16 vaccines in mice. Contact mail: darya_avdoshina@mail.ru

(11) Isaguliants Maria (Gamaleya Research Center for Epidemiology and Microbiology, Moscow, Russia). Resume on informed design and experimental testing of vaccines against papilloma virus type 16 for HIV infected men and women. Contact mail: Maria Isaguliants maria.issagouliantis@ki.se

18.40-20.00 Papilloma Viruses, molecular mechanisms of pathogenicity

(12) Vonsky Maxim & Isaguliants Maria (D.I. Mendeleev All-Russian Institute for Metrology, St Petersburg, Russia, and Gamaleya Research Center for Epidemiology and Microbiology, Moscow, Russia) Genomic instability and detection of exosomal and integrated forms for HPV 16 in the cervical squamous cell carcinomas in women infected with HIV-1 and M. tuberculosis. Contact mail: Maxim Vonsky <m.vonsky@gmail.com>

(13) Starita Noemy, Buonaguro Franco M (Molecular Biology and Viral Oncology Unit, Istituto Nazionale Tumori IRCCS Fond Pascale, Napoli, Italy) Detection of HPV infection and TERT promoter mutations in head and neck cancer. Contact mail: f.buonaguro@istitutotumori.na.it <f.buonaguro@istitutotumori.na.it>

(14) Chowdhury Sona (Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA, USA) Programmed Cell Death Protein 1 (Pd-1) and Programmed Cell Death Ligand 1 (Pd-L1) expression profile in primary and metastatic cervical cancer tissue. Contact mail: Sona.Chowdhury@ucsf.edu <Sona.Chowdhury@ucsf.edu>

(15) Joel Palefsky (Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA, USA) HPV distribution in benign, high-grade squamous intraepithelial lesions (HSIL) and squamous cell cancer (SCC) of the anus according to HIV status. Contact mail: Palefsky, Joel <Joel.Palefsky@ucsf.edu>

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